Offering the opportunity to relax by Aegean Sea, which is nearly a 5-minute stroll away, the 3-star Zefiros Beach Hotel Mykali offers 43 rooms and a swimming pool onsite. Featuring a restaurant, this Mykali hotel is 4.7 km from the Pythagorean port.

The centre of Mykali can be reached in 5 minutes' walk of the hotel, and such cultural venues as the Archaeological Museum of Vathy are approximately a 15-minute ride away. The Kallisti Gallery is also located within a 6-km distance of the Zefiros Mykali. The nearby notable religious buildings include the clifftop Monastery of Panagia Spiliani, around a 10-minute ride from the accommodation. For those travelling from afar, Samos airport is 15 minutes' drive away.

The rooms comprise a balcony and a seating area complete with air conditioning, as well as a flat-screen TV with satellite channels.