Situated only 1.1 km from the Archaeological Museum of Piraeus and approximately a 5-minute walk from the Catholic Church of St. Paul, the smoke-free Twinn Downtown Piraeus, Santikos Collection hotel features a banquet hall for various purposes. This 3-star hotel provides Wi-Fi in public areas.

Saint Paul School is located about 200 metres from the hotel, and such natural sites as the Andreas Papandreou Park is about 10 minutes' drive away. The Flisvos Marina is 3.6 km from the Twinn Downtown Piraeus, Santikos Collection, while Eleftherios Venizelos airport is 45 km from it. The area offers shopping experiences such as Art Prisma Store, which is in the vicinity of the property. Afetiria - Agios Spyridon bus stop is also within 10 minutes' walk of this Piraeus hotel.

Twinn Downtown Piraeus, Santikos Collection hotel invites guests to 33 air-conditioned rooms with views of the city and comforts like climate control. The bathroom features a separate toilet and a shower, along with hairdryers and towels.

You can have a daily American breakfast on site. Drinks are available at the lobby bar. The bar area includes a lounge. Chalki is located next to the Twinn Downtown Piraeus, Santikos Collection and serves Greek dishes, a few steps from the property.