Situated 3.3 km from the Thera Volcano, Sepal Residence Fira hotel features an archaeological museum.

The MATI Art Gallery is located just around the corner from the hotel, and Santorini International airport is approximately a 10-minute drive away. The Byzantine Castle Ruins is around 15 minutes by car from this Fira hotel, while Taxi bus stop is nearly 10 minutes' walk away. There is the Athinios Port 3.8 km from the Sepal Residence Fira.

The rooms feature air conditioning, along with a flat-screen TV with satellite channels for guests' utmost comfort.

Zafora Restaurant is located next to the property and serves Greek dishes, a few moments from the property.