Situated around a 5-minute walk from the Church of Agio Christodoulos, Hotel Palladion Karterados offers a sundeck, chaise longues, and a shared lounge. Located fairly close to Aphrodite, the hotel features a safety deposit box and a luggage locker.

This Karterados hotel is about 5 km from Santorini International airport and 1.3 km from such cultural venues as the Megaro Gyzi Museum. The Folklore Museum is in the vicinity of the Palladion in Karterados. There is the Orthodox Metropolitan Cathedral 16 minutes' walk away, and Fira Terminal bus station is 950 m from the property.

The 6 rooms at this hotel are equipped with comforts such as air conditioning, as well as a flat-screen TV with satellite channels. A separate toilet and a shower, along with a hairdryer and bathrobes, are provided in the bathroom.

Guests may find the dessert restaurant Lixoudis Pastry Shop right near Hotel Palladion.