Nestled a mere 30 metres from Aegean Sea, the comfortable 2-star Mykali Hotel Pythagoreio offers guests both a sandy beach nearby and an outdoor swimming pool on the premises. Situated on hills, the family-owned hotel is approximately 2 km from Folklore Museum of the Nikolaos Dimitriou Foundation of Samos.

This Pythagoreio hotel has a prime location around a 15-minute drive from the Samos Wine Museum. You can find the 4000 long Aquaduct Tunnel of Eupalinos, which is a great place to explore the area, 2.3 km from the Mykali Pythagoreio. The nearby notable religious buildings include the clifftop Monastery of Panagia Spiliani, about a 10-minute ride from the accommodation. For those travelling from afar, Samos airport is 10 minutes' drive away.

Mykali Hotel welcomes guests to 58 rooms fitted with climate control as well as a flat-screen TV with satellite channels. They come with private bathrooms. The modern bathrooms include a separate toilet and a shower, along with comforts such as a hair dryer and towels. You can enjoy views of the pool.

A buffet breakfast is delivered with cheese, pancakes, and fresh fruits. The Greek restaurant overlooks the sea and pampers guests with Greek dishes. The bar serves relaxing drinks. Situated within reach of the Mykali, the seafood restaurant Glicorisa Beach Bar Restaurant offers a Greek menu.