The 3-star Mesanto Luxury Suites Megalochori hotel is situated near the beach district of Megalochori, nearly a 10-minute walk from the Santorini Horse Riding. The hotel is 4.3 km from the Nea Kameni Volcanic Park and provides guests with an outdoor hot tub and a Jacuzzi.

This hotel enjoys a perfect setting in the very heart of Megalochori. The Museum of Prehistoric Thira is right near the Mesanto Megalochori, while Venetsanos bus stop is about a 5-minute walk away. No matter the religion, travellers prefer to visit the photographed Three Bells of Fira Church, a popular place of worship located 4.8 km from the accommodation. For those travelling from afar, Santorini International airport is 10 minutes' drive away.

The rooms comprise an adjoining terrace and a dressing room complete with an ironing set and an air conditioner, as well as a flat-screen TV with satellite channels. They are furnished with sound-proofed windows, and also come with coffee and tea making facilities. Bathroom amenities include a separate toilet and a shower, along with comforts such as hairdryers and towels.

Each morning, the Mesanto serves a continental breakfast. The fast food restaurant To Steki tou Nikola is in close proximity to this Megalochori hotel.