Situated around a 25-minute walk from the huge 6th century fortress "Mytilene Castle", the 4-star Heliotrope Hotels Mytilene offers 4 lounges. Featuring 69 rooms with views of the sea, the hotel is in the vicinity of the New Archaeological Museum of Mytilene.

This boutique-style hotel is only 30 metres from Aegean Sea in Mytilene. Teriade Museum is within a few blocks of the property in Mytilene. The nearby notable religious buildings include the early 19th century mosque "Museum of Byzantine Art", 4.2 km from the Heliotrope Hotels. For those travelling from afar, Mytilene airport is 5 minutes' drive away.

The smoke-free rooms come with a private safe, wireless internet and a flat-screen TV with satellite channels, as well as a minibar, coffee and tea making facilities. The private bathrooms offer a separate toilet and a shower. Guests will find shower caps and towels in the bathrooms fitted with a sauna, a separate toilet, and a shower.

Heliotrope Hotels boasts a free buffet breakfast. This Mytilene hotel offers the à la carte restaurant on-site with a variety of Italian specialities. Also, there is a lounge bar featuring a lounge, and serving refreshing beverages. To Mpalkonaki is located next to the Heliotrope Hotels Mytilene and serves Greek dishes, about 5 minutes' walk away.