Situated just 500 metres from the Ermoupolis City Hall, the 4-star Ethrion Hotel Ermoupoli has an archaeological museum and 3 courtyards. Boasting access to the Ermoupolis Industrial Museum, a 16-minute stroll away, this guest house includes a summer terrace and a picnic area providing guests with air-conditioned rooms.

The Mark Vamvakaris Museum is within a 900-metre distance of the hotel, while the Lazareta is 2.2 km away. The Syros Casino is also merely 6 minutes' walk away. The Ethrion stands within a few blocks of the Saint Nicholas Church, popular with pilgrims and tourists alike. Temporary Station KTEL bus station can be found only 400 m from this accommodation.

All of the allergy-friendly rooms are appointed with a flat-screen TV with satellite channels along with coffee/tea making facilities, and some of them include a balcony and a seating area. Furnished with a writing desk, they also have soundproof windows. Guests are welcome to use a hair dryer and bath sheets in the separate bathrooms with a walk-in shower and a separate toilet. Enjoy views of the garden, while staying at the Ethrion Ermoupoli.

A continental breakfast, with different food options, is offered each morning. The lounge bar is ideal for a relaxing drink. It also features a lounge for guests' comfort. Thessalonikia Bougatsa & Pizza serves a good range of Italian food and lies fairly close to Ethrion Hotel.