The comfortable Hotel El Greco Thessaloniki is situated near an entertainment district, merely 1.2 km from the fortified White Tower of Thessaloniki. Featuring a lounge bar, a sunbathing terrace and a shared lounge, the 3-star smoke-free hotel is in proximity to Ladadika District.

The hotel is nearly 10 minutes' walk from Aegean Sea in Thessaloniki. Guests can visit the 15th - century Hamza Bey Ottoman Mosque, which is 400 metres away, and the friendly Thessaloniki Zoo which is within a 2-km distance of the El Greco. Also, Aristotelous Square is situated just a 12-minute walk away. There is Agias Sofias Square a mere 1 km away, while KTEL Nomou Thessalonikis bus station is only a few steps from the property. The hotel is around 15 minutes on foot from Thessaloniki Central train station.

Overlooking the garden, some rooms at the El Greco Thessaloniki feature sound-proofed windows furnished with a study desk. Guests will appreciate individual climate control and ironing facilities, and relax with a satellite TV and a radio. Most rooms have private bathrooms, and they come with a shower.

Specialising in Mediterranean cuisine, the Greek restaurant also features views of the city. The restaurant Sofis House is located near Hotel El Greco.