Situated nearly 5 minutes' walk from the 2-star San Efrem Aparthotel Perissa, guests can reach Holy Cross Greek Orthodox Church in no time. Offering 9 rooms, this Perissa hotel provides a swimming pool as well.

The aparthotel is not far from Akrotiri Archaeological Site, while Waterpark Santorini is merely 0.8 km away. The San Efrem Aparthotel Perissa offers proximity to natural sights like Playa de Kamari Beach (2.7 km) and Kamari Black Pebble Beach (2.8 km). The property also takes you to the subterranean Wine Museum Koutsogiannopoulos, which is about a 10-minute drive away. There is Bob's bar bus stop approximately 300 metres from the hotel.

The rooms at the accommodation have a patio and a balcony, along with air conditioning for your convenience.

While staying at San Efrem Aparthotel, guests can choose from dining options nearby, such as Dorians Bar, located around 5 minutes' walk away, or God's Garden at a 6-minute walking distance.