Located a mere 1 km from National Gallery, Amphitryon Hotel Nafplio is just a 5-minute walk from Archaeological Museum of Nauplion. Featuring 18 rooms with views of the sea, the hotel is in proximity to the early 18th-century bastioned Palamidi Citadel.

Nestled in the Nafplio Old Town district, this 5-star hotel is within a 300-metre distance of Aegean Sea. Komboloi Museum is a short way from the Amphitryon, and Arvanitia Beach is about 1.1 km away. Guests will also enjoy proximity to Argolic Gulf, situated 300 metres away. The nearby cultural experience includes the heritage museum "Peloponnesian Folklore Foundation", which is 13 minutes' walk away. The nearest bus stop is TO Karathona beach 0.6 km away.

Along with a flat-screen TV with satellite channels, the soundproof rooms offer a minibar, and marble bathrooms with a spa bathtub, a shower booth, and a separate toilet. They come with marble bathrooms. As the Amphitryon Nafplio overlooks Bourtzi, guests can enjoy a wonderful view from their rooms.

This property serves an American breakfast. The hotel features a library bar and Circle restaurant serving Greek cuisine. The accommodation has a Greek restaurant for on-site dining with ocean views. The onsite bar has a lounge and is decorated with an open fireplace.